![m-PEG (methoxy polyethylene glycol) structure](https://www.ambiopharm.com/wp-content/uploads/2022/04/PEG-1-300x175.png)
We make several PEGylated peptides at large commercial scale. PEGylation adds a polyethylene glycol (PEG) polymer to target molecules through a covalent attachment. This may be via an amide linkage to a Lys or Cys residue via a maleimide linkage. PEGylation may help to enhance a peptide’s therapeutic properties by masking them from the host’s immune system, increasing their solubility (for hydrophobic drugs), and bioavailability. PEGS>20kD can slow renal clearance prolonging the circulating half-life time of the product in the host