Biologically Active Peptides

Biologically active peptides are typically from 5 to approximately 70 amino acid residues in length. In many cases, the peptide chain is stabilized with covalent crosslinks (for example, disulfide bonds) to maintain their desired biological activities.

These activities may include analgesic, antidiabetic, antihormonal, antimicrobial, anti-inflammatory, antioxidant, anti-hypertensive, antithrombotic, and laxative effects. With low toxicity and high specificity, these peptides are routinely used in the pharmaceutical, food, cosmetic, veterinary, and diagnostic industries.

Some common categories of biologically active peptides include:

  • Angiotensins and other cardiovascular peptides
  • Antimicrobial peptides and host defense peptides (including defensins, LL-37)
  • Cell-penetrating peptides (including TAT peptides)
  • Enzyme inhibitors and substrates
  • Glucagon-like peptides (GLP-1, GLP-2) and GLP-1 agonists and antagonists
  • Hepcidins
  • Neuropeptides
  • RGD peptides (which include linear and cyclic)
  • Receptor agonists and antagonists
  • Venom and toxin peptides

AmbioPharm chemically synthesizes biologically active peptides tailored to our customer’s needs and specifications. Our processes are efficient and utilize state-of-the art manufacturing methods and equipment in our facilities in the USA and Shanghai and can accommodate commercial scales.  Contact us to request a quote or learn more about our capabilities.

FDA Compliant

All our processes comply with cGMP (Current Good Manufacturing Practice) regulations as required by the FDA.  These regulations assure proper design, monitoring, and control of manufacturing processes and facilities. 

AmbioPharm’s quality systems assures the identity, strength, quality, and purity of the products we manufacture. 

Our Quality Control Department continuously monitors production.  Using quality controls, scientifically sound design practices, processing methods, and testing procedures, we are continuously developing and improving on all of our processes.

CEM Liberty Pro Microwave SPPS Synthesizer

Peptide Manufacturing in the USA

Our peptide manufacturing facilities in North Augusta, South Carolina use cGMP methods for quality.

  • Purification scale from grams to 30kg per batch
  • Preparative HPLC columns up to 100cm
  • Lyophilization capacity up to 1,000L

Peptide Manufacturing in China

Our facilities in Shanghai, China also employ cGMP methods that meet FDA regulations and requirements.

  • Reactors from 20L to 5,000L
  • Continuous Flow Centrifuges
  • Vacuum ovens from 50L to 1,000L
  • Thin film evaporators
  • 500L reactor for hydrogenation
  • Up to metric tons of APIs and intermediate
  • Preparative HPLC columns up to 30cm
  • Lyophilization capacity up to 200L


For Peptide API Manufacturing and Services

Have a Peptide project?