What methods do you use to synthesize peptides?

We typically use Fmoc-tBu solid-phase peptide synthesis (SPPS), but we are also very skilled in the art of classical (solution phase or liquid phase peptide synthesis (LPPS)), and hybrid synthesis methods. Hybrid synthesis technology utilizes fully protected peptide fragments that are coupled onto resin-bound peptide fragments. For very long peptides, we may even consider native chemical ligation (NCL) approaches.

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