What purity percentage is required?

The required purity percentage depends on your specific application. AmbioPharm can synthesize peptides to >98% purity. These are some general guidelines for peptide purity requirements:

Purity Application or Use
>80% Immunological applications and polyclonal antibody production
>90%* Structure-Activity Relationships (SAR) studies, bioassays
>95%* In vitro bioassays and in vivo biological activity tests, Ph I and early Ph II
>98% Pharma-cGMP material with set impurity specifications (late PH II – Ph III and commercial)

*For peptides utilized for Toxicology studies, it is recommended to have specifications for purity on the lower end perhaps from 90 – 95%.

Interested in learning more about Peptide Manufacturing? Contact Us.